Author(s): Cui, N (Cui, Ning); Xu, MK (Xu, Mengke); Guan, M (Guan, Min); Liu, XF (Liu, Xingfang); Zeng, YP (Zeng, Yiping); Zhang, Y (Zhang, Yang)

Source: APPLIED PHYSICS EXPRESS Volume: 16 Issue: 1 Article Number: 017002 DOI: 10.35848/1882-0786/acb12c Published: JAN 1 2023

Abstract: In this letter, we focus on the relationship between modification bioparticle density (N) and biological regulation ability in extended gate HEMT (EG-HEMT) biosensors. By analyzing, we demonstrate that under the same gate electrodes size (S (g)) and concentration, N is exponentially related to the area of sensing regions (y) and has fixed exponential magnification -0.65 +/- 0.05. This formula had been demonstrated to have perfect universality when testing protein and small molecules. Finally, we apply N to the structural design of EG-HEMT biosensors and projected that 10 y structure has both high biological regulation ability of biosensors and efficient utility of chips.

Accession Number: WOS:000915687100001

ISSN: 1882-0778

eISSN: 1882-0786

Full Text: https://iopscience.iop.org/article/10.35848/1882-0786/acb12c