Author(s): Cui, N (Cui, Ning); Guan, M (Guan, Min); Xu, MK (Xu, Mengke); Fang, WH (Fang, Weihao); Zhang, Y (Zhang, Yang); Zhao, CF (Zhao, Chenfeng); Zeng, YP (Zeng, Yiping)

Source: OPTICS EXPRESS Volume: 28 Issue: 11 Pages: 16834-16844 DOI: 10.1364/OE.393397 Published: MAY 25 2020

Abstract: The terahertz (THz) metamaterial biosensor has great potential for label-free and rapid specificity testing. Here, we designed two highly sensitive structures to detect the carcinoembryonic antigen (CEA) of the cancer biomarker in early stages. There was about 29 GHz (500 ng/ml) resonance shift for CEA with an insert grate metamaterial, which was consistent with simulation results. Moreover, the concentration of CEA was gained through the relationship between the cancer marker concentration and frequency shift (Delta f). Our design and detection methods may provide a potential route for the early warning stages of cancer. (C) 2020 Optical Society of America under the terms of the OSA Open Access Publishing Agreement

Accession Number: WOS:000542303000086

PubMed ID: 32549497

ISSN: 1094-4087

Full Text: https://www.osapublishing.org/oe/abstract.cfm?uri=oe-28-11-16834